Molecular Basis of Disease

This course will examine cellular and molecular mechanisms that play a major role in causing dysfunction of a variety of relevant tissues under a number of chronic conditions including aging, cardiovascular disease, diabetes, cancer, autoimmune disorders, neurodegenerative conditions, and muscular diseases. Topics to be covered include satellite cells/stem cells, apoptosis and necrosis, mitochondrial dysfunction, mitochondrial DNA, oxidative stress, autophagy and protein degradation, and inflammation.